E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.
The E2F1 transcription factor regulates cell proliferation and apoptosis through the control of a considerable variety of target genes.Previous work has detailed the Valves role of other transcription factors in mediating the specificity of E2F function.Here we identify the NF-YB transcription factor as a novel direct E2F1 target.Genome-wide expres